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00_Introduction/README.md

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@@ -13,6 +13,9 @@ Statistical genetics is a field that combines **genetics**, **statistics**, and
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- Understand the **genetic architecture** of **complex traits**
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- Predict disease risk based on **genetic information**
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![Satistical genetics](images/statistical_genetics.jpg)
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!!! info "Key concepts in statistical genetics"
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- **Genetic variation**: Differences in DNA sequences among individuals

08_LDSC/README.md

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- $h^2$ : observed-scale heritability
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- $a$ : the effect of confounding factors, including cryptic relatedness and population stratification.
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![LD Score Regression Example](images/ld_score_example.jpg)
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For more details of LD score regression, please refer to :
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- Bulik-Sullivan, Brendan K., et al. "LD Score regression distinguishes confounding from polygenicity in genome-wide association studies." Nature genetics 47.3 (2015): 291-295.
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docs/00_Introduction.md

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@@ -13,6 +13,9 @@ Statistical genetics is a field that combines **genetics**, **statistics**, and
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- Understand the **genetic architecture** of **complex traits**
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- Predict disease risk based on **genetic information**
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![Satistical genetics](images/statistical_genetics.jpg)
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!!! info "Key concepts in statistical genetics"
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- **Genetic variation**: Differences in DNA sequences among individuals

docs/08_LDSC.md

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- $h^2$ : observed-scale heritability
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- $a$ : the effect of confounding factors, including cryptic relatedness and population stratification.
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![LD Score Regression Example](images/ld_score_example.jpg)
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For more details of LD score regression, please refer to :
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- Bulik-Sullivan, Brendan K., et al. "LD Score regression distinguishes confounding from polygenicity in genome-wide association studies." Nature genetics 47.3 (2015): 291-295.
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docs/images/ld_score_example.jpg

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