diff --git a/internal/devbox/devbox.go b/internal/devbox/devbox.go
index 43ce1f2935c..9b9f01440d2 100644
--- a/internal/devbox/devbox.go
+++ b/internal/devbox/devbox.go
@@ -1065,6 +1065,10 @@ var ignoreCurrentEnvVar = map[string]bool{
 
 	// The "_" variable is read-only, so we ignore it to avoid attempting to write it later.
 	"_": true,
+
+	// PROFILEREAD is read-only in SUSE/openSUSE to prevent duplicate processing
+	// of system and user environment variables.
+	"PROFILEREAD": true,
 }
 
 // ignoreDevEnvVar contains environment variables that Devbox should remove from