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fix q2 formula according to paper. recalculate rate constants after applying the opiates correction.#247

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fix q2 formula according to paper. recalculate rate constants after applying the opiates correction.#247
jaj42 wants to merge 1 commit intoJMathiszig-Lee:masterfrom
jaj42:jjoachim

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@jaj42 jaj42 commented Nov 12, 2025

In the paper, as well as in the NONMEM code, age maturation is not divided by reference age maturation for calculation of Q2.
The with_opiates() function calls from_clearances() which will recalculate the rate constants, but not transform them from min-1 to s-1 like setup() does.

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