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feat: egfr string + irefindex, refactor(cache): pinned/unpinned#59

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tristan-f-r wants to merge 18 commits intomainfrom
egfr-new-interactome
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feat: egfr string + irefindex, refactor(cache): pinned/unpinned#59
tristan-f-r wants to merge 18 commits intomainfrom
egfr-new-interactome

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@tristan-f-r tristan-f-r commented Feb 18, 2026

For the new EGFR interactome. We also:

  • bundle the old EGFR iRefIndex interactome.
  • Change cache to handle unpinned/pinned versions (in a later PR, we will actively warn for when unpinned files do not match our cached counterparts, to recommend that certain files get updated)
  • Somewhat refactors diseases to be clearer.

We get higher counts of UniProt -> STRING interactions than usual, though I haven't trimmed it yet.
@tristan-f-r tristan-f-r added the dataset Mutating datasets in any way. label Feb 18, 2026
@tristan-f-r tristan-f-r changed the title feat: egfr interactome feat: egfr string interactome Feb 18, 2026
@tristan-f-r tristan-f-r marked this pull request as ready for review February 19, 2026 00:25
@tristan-f-r tristan-f-r changed the title feat: egfr string interactome feat: egfr string + irefindex Feb 19, 2026
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From meeting: maybe don't downsample this dataset?

@tristan-f-r tristan-f-r changed the title feat: egfr string + irefindex feat: egfr string + irefindex, refactor: cache pinned/unpinned Feb 23, 2026
@tristan-f-r tristan-f-r changed the title feat: egfr string + irefindex, refactor: cache pinned/unpinned feat: egfr string + irefindex, refactor(cache): pinned/unpinned Feb 23, 2026
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