v1.53.0

• Update caches for human pathway interactions and mouse gene structure (#384)

v1.52.0

• Improve configurability for interactive pathways (#383)

v1.51.0

This enables showing clinical variants in Gene Leads, and new annotation rendering modes.

Show_clinical_variants_on_gene_models__Ideogram_2025-02-18.mov

Changes:

• Add ClinVar cache pipeline for variant health data (#378)
• Add placement and span options (#379, thank you @chaisarina and @christianfares!)
• Show clinical variants on gene models (#380)
• Enable static draw for pathways (#381)

v1.50.0

• Simplify configuration for Gene Leads (#377)

v1.49.0

Updates:

• Enable searching genes by Ensembl ID (#376)
• Avoid hiding tooltip on first hover of previous clicked annotation (#375)

Here's a video on Gene Leads Ideogram. Unmute it by clicking the speaker icon at lower right. Compare to the equivalent video from 2 years ago, and notice major improvements like:

• Distribution curves for gene expression by tissue
• Better molecular diagrams for proteins
• Pathway diagrams

Gene_leads_ideogram_2024.mov

v1.48.0

• Show more relevant interacting genes (#374)

v1.47.0

• Add observable event for draw completion in pathway diagrams (#371)

v1.46.0

This enables biochemical pathway diagrams for interacting genes, giving deep functional insight into cell circuits.

Pathway_diagrams__Ideogram_2024-08-09.mov

Try it out yourself! See #370 for details.

v1.45.1

• Fix URL code for tissue cache range fetch (#368)

v1.45.0

This release integrates gene-tissue expression visualizations into Ideogram. Data comes from GTEx. Here's how it looks!

Release_1-45-0__IdeogramJS_2024-01-15.mov

Links below -- particularly #365, #366, and #367 -- describe the enhancements in detail.

Changes

• Ensure top max-expressing tissue is shown, robustify curve shift (#367)
• Reframe tissue curves on hover, enriching expression comparison (#366)
• Show gene expression distribution by tissue (#365)
• Enhance gene leads tooltip: plot reference expression by tissue (#364)
• Show top expressed tissues by gene (#363)
• Show if gene is among top expressed in tissue (#362)