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Add plink_gwas_regenie subworkflow#11938

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lyh970817 wants to merge 9 commits into
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lyh970817:subworkflows/regenie-gwas-create
Draft

Add plink_gwas_regenie subworkflow#11938
lyh970817 wants to merge 9 commits into
nf-core:masterfrom
lyh970817:subworkflows/regenie-gwas-create

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Description

Adds the plink_gwas_regenie subworkflow to run REGENIE Step 1 model fitting followed by Step 2 association testing from PLINK-format genotype bundles.

This subworkflow composes plink_fit_regenie with regenie/step2, supports standard and chunked Step 1 execution, and supports multiple Step 2 genotype shards sharing the same analysis meta.id.

Draft dependencies: this PR depends on #11768 for regenie/runl1 and #11937 for plink_fit_regenie.

PR checklist

  • This comment contains a description of changes (with reason).
  • If you've fixed a bug or added code that should be tested, add tests!
  • Remove all TODO statements.
  • Broadcast software version numbers to topic: versions - See version_topics
  • Follow the naming conventions.
  • Follow the parameters requirements.
  • Follow the input/output options guidelines.
  • Ensure that the test works with either Docker / Singularity. Conda CI tests can be quite flaky:
    • For subworkflows:
      • nf-core subworkflows test plink_gwas_regenie --profile docker --dir .
      • nf-core subworkflows test plink_gwas_regenie --profile singularity
      • nf-core subworkflows test plink_gwas_regenie --profile conda

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